Calcium Antagonists in Clinical Medicine by Murray Epstein

Cover of: Calcium Antagonists in Clinical Medicine | Murray Epstein

Published by Hanley & Belfus .

Written in English

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  • Clinical & Internal Medicine,
  • Medical,
  • Cardiovascular Diseases,
  • Clinical Pharmacology,
  • Medical / Nursing,
  • Therapeutic use,
  • Cardiology,
  • Internal Medicine,
  • Pharmacology,
  • Antagonists,
  • Calcium

Book details

The Physical Object
Number of Pages700
ID Numbers
Open LibraryOL9404369M
ISBN 101560534966
ISBN 109781560534969

Download Calcium Antagonists in Clinical Medicine

Calcium Antagonists in Clinical Medicine Hardcover – Octo by Murray Epstein MD FACP (Author) See all formats and editions Hide other formats and editions. Price New from Used from Hardcover "Please retry" $ $ $ Hardcover $ Author: Murray Epstein Md Facp.

ISBN: OCLC Number: Description: viii, pages: illustrations ; 24 cm: Contents: Biochemical and pharmacological differences among calcium antagonists: clinical implications / David J. Triggle --Calcium function in vascular smooth muscle and its relationship to hypertension / Jeffrey L.

Ram, Paul R. Standley, James R. Sowers --Pharmacokinetics of calcium. [et al.] --Effects of Calcium Antagonists on Vasoactive Hormones / Jose Tunon, Nieves Tarin, Jesus Egido The Clinical Utility of Calcium Antagonists in Renal Transplant Recipients / Matthew R.

Weir --Calcium Antagonists and the Kidney: Implications for Renal Protection / Murray Epstein --Ambulatory Blood Pressure: Implications for Renal. Calcium Antagonists in Clinical Medicine [Murray Epstein] on *FREE* shipping on qualifying offers.

Univ. of Miami, FL. Experts review the current state of knowledge of calcium antagonists. Extensive references. 46 contributors. Calcium antagonists are commonly used antihypertensive drugs among prescribing physicians. 1–4 In the Cardiovascular Health Study, there was an increase in the use of calcium antagonists from 14% in to 36% in among participants aged 65 years or older (Figure ).

4 The growth of calcium antagonist use has been attributed to increased drug advertising. 5 Their use has not. Find many great new & used options and get the best deals for Calcium Antagonists in Clinical Medicine by Murray Epstein (, Hardcover, Revised) at the best online prices at.

Although several proceedings of symposia on calcium channel blockers have been published, there has been no recent textbook on the clinical aspects of calcium channel blocker therapy in clinical medicine.

This chapter book fills that : Mihai Gheorghiade. Although the importance of calcium (Ca 2+) in the maintenance of cardiac contractility was recognized as early asthe critical role of the ion in the contractile process in skeletal, cardiac, and smooth muscle has only been established within the last three decades.

As the complexity of the pharmacological actions of the Ca 2+ channel inhibitors grows, there is a continued need to. Calcium channel blockers lower blood pressure and treat other conditions such as chest pain and an irregular heartbeat. Calcium channel blockers lower your blood pressure by preventing calcium from entering the cells of your heart and arteries.

Calcium causes the heart and arteries to contract more strongly. By blocking calcium, calcium channel. Open Library is an open, editable library catalog, building towards a web page for every book ever published. Calcium Antagonists in Clinical Medicine by Murray Epstein; 2 editions; First published in Middleton E., Jr Role of calcium and calcium antagonists in airway function.

Eur J Respir Dis Suppl. ; (Pt 1)– Middleton E, Jr, Drzewiecki G, Triggle D. Effects of smooth muscle calcium antagonists on human basophil histamine release.

Biochem Pharmacol. Oct; 30 (20)–Cited by: Calcium channel blockers (CCB), calcium channel antagonists or calcium antagonists are a group of medications that disrupt the movement of calcium (Ca Calcium Antagonists in Clinical Medicine book through calcium channels.

Calcium channel blockers are used as antihypertensive drugs, i.e., as medications to decrease blood pressure in patients with are particularly effective against large vessel stiffness, Calcium Antagonists in Clinical Medicine book of the ATC code: C Part of the Developments in Cardiovascular Medicine book series (DICM, volume 39) Log in to check access.

Buy eBook. USD Phospholipase A 2 Activity by Calcium Antagonists: Evidence for Intracellular Effects of Calcium Slow Channel Blockers. The book also includes important uses of Ca 2+ antagonists in novel areas of interest such as the gastrointestinal tract, renal protection and multi-drug resistance.

Keywords atherosclerosis calcium cardiovascular clinical research drug resistance heart hypertension. Calcium antagonists in clinical medicine (Book, This is a review of the multitude of clinical applications already known and in practice for the class of drugs called calcium antagonists or calcium blockers (Diltiazem, Nifedipine, Verapamil, etc).

Calcium antagonists in clinical medicine (Book, US National Library of Medicine. Plain language summary. There is no evidence to suggest that calcium antagonists have a useful effect on seizures. Nearly a third of people with epilepsy become resistant to antiepileptic drugs. Older drugs do not prevent seizures for everyone, and they have adverse effects.

A range of new drugs have been tested as 'add‐on' treatments to try and improve the results from antiepileptic drugs. Calcium Antagonists: Pharmacology and Clinical Research (Medical Science Symposia Series) Drugs Looking for Diseases: Innovative Drug Research and the Development of the Beta Blockers and the Calcium Antagonists (Developments in Cardiovascular Medicine) Calcium Antagonists and.

Magnesium, the fourth most abundant metal in living organisms, is distributed in three major compartments in the body: 65 per cent in the mineral phase of skeleton, 34 per cent in the intracellular Cited by: Innovative Drug Research and the Development of the Beta Blockers and the Calcium Antagonists.

Authors The controlled clinical trial — A model for the intricate relationships between clinical medicine and drug research *immediately available upon purchase as print book shipments may be delayed due to the COVID crisis.

ebook access. When taken together, all these differences distinguish the preferential clinical utilization of one of these compounds for a given cardiovascular pathology. AB - The majority of calcium antagonists used clinically belong to three distinct chemical classes: the phenylalkylamines, the dihydropyridines, and the by: Calcium Antagonists in Clinical Medicine Murray Epstein, M.D., F.A.C.P.

Professor of Medicine University of Miami School of Medicine Attending Physician Veterans Administration Medical Center Jackson Memorial Medical Center Miami, Florida HANLEY & BELFUS, INC./Philadelphia MOSBY-YEAR BOOK, INC./St.

Louis • Baltimore • Boston. calcium channel blocker: [ blok´er ] something that blocks or obstructs a passage or activity; see also antagonist and blocking agent.

α-blocker alpha-adrenergic blocking agent. β-blocker (beta-blocker) beta-adrenergic blocking agent. calcium channel blocker calcium channel blocking agent.

potassium channel blocker potassium channel. Dihydropyridine L-type Ca 2+ channel antagonists significantly block the slow apamin-insensitive AHP in hippocampal pyramidal neurons.

This is shown in Figure 2, in which the selective effects of the L-type channel antagonists are seen together with the lack of effect of blockers of other Ca 2+ channel subtypes.

The block of the slow AHP in hippocampal CA1 neurons in a slice preparation by the. Myocardial Protection by Calcium Antagonists by Lionel H. Opie,available at Book Depository with free delivery worldwide.4/5(1). Drugs Looking for Diseases: Innovative Drug Research and the Development of the Beta Blockers and the Calcium Antagonists ‹ PREV ARTICLE notably the first chapter with its short history of clinical trials and the second chapter with its section on clinical taxonomy.

The entire book serves as an exhaustive history of the pharmacologic. Calcium channel and beta-adrenergic receptor antagonists are common pharma-ceutical agents with multiple overlapping clinical indications. When used appropriately, these agents are safe and overdose,however,these agents have the potential for serious morbidity.

Calcium channel blockers and beta blockers share similar physio. Calcium Antagonists a Good Alternative. It is important to individualize drug treatment for patients with hypertension. [] Therefore, although diuretics and -blockers will often be the therapy of. Calcium Channel Blockers Definition Calcium channel blockers are medicines that slow the movement of calcium into the cells of the heart and blood vessels.

This, in turn, relaxes blood vessels, increases the supply of oxygen-rich blood to the heart, and reduces the heart's workload. Purpose Calcium channel blockers are used to treat high blood pressure. Various pharmacologic agents have been used for perioperative BP control in pediatric patients, including sodium nitroprusside, nitroglycerin, β-adrenergic antagonists, fenoldopam, and calcium channel antagonists.

Of the calcium antagonists, the majority of the clinical experience remains with the dihydropyridine nicardipine. Calcium channel blockers (CCBs) are drugs that bind to and block the L-type calcium channel. The L-type channels are the predominant calcium channels in the myocardium and the vascular smooth muscles.

By blocking these channels, CCBs cause peripheral arterial vasodilation and myocardial depression, which leads to a drop in blood pressure and. The strong clinical bias of the present book should be complimented by further reading of books slanted towards fundamentals.

One of the most important and recent of these is that by Dr Winifred Nayler (Calcium Antagonists, Academic Press, ). That book should be basic for essential background knowledge in the area of calcium antagonists.

This causes the blood vessels to relax and widen, which allows the blood to flow more easily and lowers blood pressure. Some calcium antagonists may also slow the heartbeat. Calcium antagonists are used to treat high blood pressure, chest pain (angina), abnormal heartbeat (arrhythmia), and several other conditions.

Also called calcium channel. Calcium channels are a common component of the membranes of a wide range of excitable cells, and their presence is crucial to the functioning of these cells.

This book presents a current review of the biophysics, physiology, pharmacology, and clinical role of calcium channels. H2 antagonists block histamine-induced gastric acid secretion from the parietal cells of the gastric mucosa (lining of the stomach).

H2 antagonists are used to treat gastroesophageal reflux disease (GERD), gastrointestinal ulcers and other gastrointestinal hypersecretory conditions. Always consult your healthcare provider to ensure the. Calcium-channel blockers restrict how much calcium can enter the muscle cells in your blood vessels.

These then relax, causing the arteries to widen (this is called vasodilation). This helps to lower your blood pressure. Calcium-channel blockers also prevent angina by. Ca2+ homeostasis is achieved through a fine balance among three main organs: the intestine, the kidney, and bone.

Blood levels of Ca2+ are accurately tuned through the Ca2+ sensing receptors and regulated by several hormones, including parathyroid hormone (PTH), active vitamin D, and calcitonin. The most recent findings in Ca2+ handling are described. The role of the Ca2+ sensing receptor, as Author: Francesco Trepiccione.

Calcium antagonists decrease calcium entry through L-type cellular calcium channels, acting primarily on vascular smooth muscle and the heart.

They cause coronary and peripheral vasodilation, reduced cardiac contractility, slowed atrioventricular nodal conduction, and depressed sinus node activity. Define calcium antagonist. calcium antagonist synonyms, calcium antagonist pronunciation, calcium antagonist translation, English dictionary definition of calcium antagonist.

n another name for calcium channel blocker (Medicine) another name for calcium channel blocker. Want to thank TFD for its existence. they will usually also develop. is a rapid access, point-of-care medical reference for primary care and emergency clinicians.

Started inthis collection now contains interlinked topic pages divided into a tree of 31 specialty books and chapters. Content is updated monthly with. In the fields of medicine, drug discovery is the process by which new candidate medications are discovered.

This book demonstrates that various expertise are essential for drug discovery including synthetic or natural drugs, clinical pharmacology, receptor identification, drug metabolism, pharmacodynamic and pharmacokinetic research.

Click on the book chapter title to read by: Heart failure (HF) is a heterogeneous clinical syndrome which may be characterized by a variety of phenotypic changes, many of which have been linked to abnormalities in the intracellular calcium(Ca2+) signal.

These range from mechanical dysfunction, usually characterized by reduced systolic contractile function, to electrophysiological dysfunction including QT interval prolongation, an.The effect of calcium antagonists on heart muscle and blood circulation is the reason that they have found widespread clinical application for a number of years.

Less well known, in contrast, is the effect this group of substances has on the kidneys, both on kidney cells and the blood flow through the : Springer Berlin Heidelberg.

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